Quest for a Unifying Diagnosis: Felty Syndrome?

Presentation of three cases followed up with a diagnosis of Felty syndrome.

An effective treatment strategy for Felty syndrome (FS) has not been developed so far. In this article, three cases with FS, who responded to different treatment modalities, have been presented. Case 1 was a 52-year-old male patient who initially received methotrexate, and then, he was switched to granulocyte colony-stimulating factor (G-CSF) and cyclosporine treatment when his neutropenia was ...

Splenic neutropenia in the Felty syndrome.

By H. E. HUTCHISON AND W. D. ALEXANDER T HE POSSIBILITY that overactivity of the spleen might cause neutropemsia, mentiomsed by Bauer us 1899,’ was discussed at lemsgth by Framskm who drew attentious to the close associatious betweeus splemsomegaly of diverse etiology amid iseutropemsia; that was its 1916, the year its which Kaztselsonm first reported rise of the platelet coumit followiusg remo...

Felty Syndrome Associated with Biliary Cirrhosis - a Case Report

The case presented herein is of a 32-year patient who was diagnosed in 2005 with primitive biliary cirrhosis stage II based on clinical and laboratory examinations, including hepatic biopsy. In 2007, the patient complained of joint pain and morning stiffness. At that time, tests indicated a high titer of rheumatoid factor (RF), and specific antibodies of rheumatoid arthritis. Therefore the pati...

A Unifying Theory for Psychiatric Diagnosis

Unifying Time and Uncertainty for Diagnosis 1

Existing models of diagnosis have not uni ed the notions of time, uncertainty and abduction which are necessary in domains such as clinical diagnosis, dynamic systems modeling, and fault diagnosis. We present a new approach which models information through linear constraints and nd that many aspects of our knowledge-base and inferencing mechanism are naturally suited towards these constraints. ...